Opiate Addiction and its Confounding Crisis

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Opiate addiction and cocaine addiction: underlying molecular neurobiology and genetics.

Addictive diseases, including addiction to heroin, prescription opioids, or cocaine, pose massive personal and public health costs. Addictions are chronic relapsing diseases of the brain caused by drug-induced direct effects and persisting neuroadaptations at the epigenetic, mRNA, neuropeptide, neurotransmitter, or protein levels. These neuroadaptations, which can be specific to drug type, and ...

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Opiate addiction is a chronically relapsing disorder that is characterized by compulsive drug taking, an inability to limit intake, and bouts of intense drug craving that can be precipitated by the mere presence of people, places, or objects previously associated with drug use. Although knowledge of the neural mechanisms that underlie the transition from casual drug use to addiction is still in...

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Genetic Aspects of Opiate Addiction

By Arthur Falek, Ph.D. What is known about the genetic aspects of opiate addiction? Opiates such as heroin and dilaudid are drugs which have long been known to relieve or depress pain but increased consumption frequently result in uncontrolled drug use and addiction. These properties of opiates led to the discovery that there are specific opiate receptors in the brain and that the central nervo...

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ژورنال

عنوان ژورنال: Berkeley Scientific Journal

سال: 2018

ISSN: 2373-8146,1097-0967

DOI: 10.5070/bs3231042198